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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Can inhaled prostacyclin stimulate surfactant in ELBW infants?

Journal of Perinatology volume 27, pages 724–726 (2007)Cite this article

Abstract

Respiratory distress syndrome (RDS) causes significant hypoxia in extremely low birth weight (ELBW) infants. We report an ELBW infant with RDS and pulmonary hypertension whose hypoxia did not respond to inhaled nitric oxide but improved with inhaled prostacyclin. We propose that inhaled prostacyclin alleviated the hypoxia by stimulating surfactant secretion.

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Acknowledgements

The authors would like to thank John Belmont, PhD, for his help with the manuscript especially with Figure 1 and Leoni Mattioli, MD, for his excellent suggestions.

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Authors and Affiliations

  1. Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS, USA

    K Olmsted, O Oluola, A Parthiban & T Raghuveer

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  1. K Olmsted
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  2. O Oluola
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  3. A Parthiban
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  4. T Raghuveer
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Correspondence to T Raghuveer.

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Olmsted, K., Oluola, O., Parthiban, A. et al. Can inhaled prostacyclin stimulate surfactant in ELBW infants?. J Perinatol 27, 724–726 (2007). https://doi.org/10.1038/sj.jp.7211811

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  • DOI: https://doi.org/10.1038/sj.jp.7211811

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