I read with interest Ah Kiné and Adams'1 report of marked anterior uveitis following streptokinase infusion. I have been involved with a similar case recently that was bilateral. The onset was also within 12 h of the streptokinase infusion, and the patient had bilateral hypopyons. I agree that the rapidity of the immune response suggests previous exposure to streptococcal antigen.
When I presented this case at our regional postgraduate meeting, it transpired that two other cases were known within the region in the preceding 12 months. It seems likely that anterior uveitis secondary to streptokinase infusion is more common than is generally recognised.
References
Ah Kiné D, Adams W . ‘Hyperacute' unilateral anterior uveitis and secondary glaucoma following streptokinase infusion. Eye 2001; 15: 804–805.
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Beare, N. ‘Hyperacute’ unilateral anterior uveitis and secondary glaucoma following streptokinase infusion. Eye 18, 111 (2004). https://doi.org/10.1038/sj.eye.6700537
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DOI: https://doi.org/10.1038/sj.eye.6700537