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Salvage cryosurgery for locally recurrent prostate cancer following radiotherapy

Prostate Cancer and Prostatic Diseases volume 8, pages 31–35 (2005)Cite this article

Abstract

The popularity of radiotherapy as a minimally invasive treatment for prostate cancer is increasing. Despite advancements in radiation delivery, a number of patients will fail treatment. Salvage radical prostatectomy has been the main therapeutic option for locally recurrent radiation failure prostate cancer with curative intent. The operation is technically difficult to perform and associated with significant comorbidities. Salvage cryotherapy has emerged as a minimally invasive alternative option. In this article, we review the role of cryotherapy in recurrent prostate cancer and compare its outcome with salvage radical prostatectomy.

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References

  1. Stamey TA et al. Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate. N Eng J Med 1987; 317: 909–916.

    Article  CAS  Google Scholar 

  2. Oesterling JE . Prostate-specific antigen. A critical assessment of the most useful tumour marker for adenocarcinoma of the prostate. J Urol 1991; 145: 907–923.

    Article  CAS  Google Scholar 

  3. Wheeler JA, Zagras GK, Ayala AG . Dedifferentiation of locally recurrent prostate cancer after radiation therapy: evidence for tumour progression. Cancer 1993; 71: 3783–3787.

    Article  CAS  Google Scholar 

  4. Younes E et al. Value of preoperative PSA in predicting pathologic stage of patients undergoing salvage prostatectomy. Urology 1994; 43: 22–25.

    Article  CAS  Google Scholar 

  5. Hanks GE, Martz KL, Krall JM, Diamond JJ . Analysis of independent variables affecting survival after recurrence of prostate cancer. Int J Radiat Oncol Biol Phys 1989; 16: 1431–1435.

    Article  CAS  Google Scholar 

  6. Schellhammer PF, Kuban D, El-Mahdi AM . Incidence and treatment: local failure after definitive treatment of carcinoma of the prostate. Urol Clin North Am 1991; 18: 485–499.

    CAS  PubMed  Google Scholar 

  7. Kuettel MR et al. Radiation-induced neoplastic transformation of human prostate epithelial cells. Cancer Res 1996; 56: 5–10.

    CAS  PubMed  Google Scholar 

  8. Rogers E et al. Salvage radical prostatectomy: outcome measured by serum prostatic specific antigen levels. J Urol 1995; 153: 104–110.

    Article  CAS  Google Scholar 

  9. Amling CL et al. Deoxyribonucleic acid ploidy and serum prostatic specific antigen predict outcome following salvage prostatectomy for radiation refractory prostate cancer. J Urol 1999; 161: 857–863.

    Article  CAS  Google Scholar 

  10. Arnott J . Practical illustrations of the remedial efficacy of a very low or anaesthetic temperature-I in cancer. Lancet 1850; 2: 257–259.

    Article  Google Scholar 

  11. Pusey WA . The use of carbon dioxide snow in the treatment of nevi and other lesions of the skin: a preliminary report. JAMA 1907; 49: 1354–1356.

    Article  Google Scholar 

  12. Allington HV . Liquid nitrogen in the treatment of skin diseases. Calif Med 1950; 72: 153–155.

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Cooper IS, Lee AJ . Cryostatic congelation: a system for producing a limited controlled region of cooling or freezing of biologic tissues. J Nerv Ment Dis 1961; 133: 259–263.

    Article  CAS  Google Scholar 

  14. Gonder MJ, Soanes WA, Shulman S . Cryosurgical treatment of the prostate. Invest Urol 1966; 3: 372–378.

    CAS  PubMed  Google Scholar 

  15. Flocks RH, Nelson CM, Boatman DL . Perineal cryosurgery for prostatic carcinoma. J Urol 1972; 108: 933–935.

    Article  CAS  Google Scholar 

  16. Megalli MR, Gursel EO, Veenema RJ . Closed perineal cryosurgery in prostate cancer. New probe and technique. Urology 1974; 4: 220–222.

    Article  CAS  Google Scholar 

  17. Onik G et al. Transrectal ultrasound-guided percutaneous radical cryosurgical ablation of the prostate. Cancer 1993; 72: 1291–1299.

    Article  CAS  Google Scholar 

  18. Onik G et al. US characteristics of frozen prostate. Radiology 1988; 168: 629–631.

    Article  CAS  Google Scholar 

  19. Lee F et al. US-guided percutaneous cryoablation of prostate cancer. Radiology 1994; 192: 769–776.

    Article  CAS  Google Scholar 

  20. Wong W et al. Cryosurgery as a treatment for prostate carcinoma: results and complications. Cancer 1997; 79: 963–974.

    Article  CAS  Google Scholar 

  21. Cohen J, Miller RJ, Shuman BA . Urethral warming catheter for use during cryoablation of the prostate. Urology 1995; 45: 861–864.

    Article  CAS  Google Scholar 

  22. Rewcastle JC et al. Consideration during clinical operation of two commercially available cryomachines. J Surg Oncol 1999; 71: 106–111.

    Article  CAS  Google Scholar 

  23. Tatsutani K, Rubinsky M, Onik G, Dahiya R . Effect of thermal variables on frozen human primary prostatic adenocarcinoma cells. Urology 1996; 48: 441–447.

    Article  CAS  Google Scholar 

  24. Patel BG, Parsons CL, Bidair M, Schmidt JD . Cryoablation for carcinoma of the prostate. J Surg Oncol 1996; 63: 256–264.

    Article  CAS  Google Scholar 

  25. Han K et al. Treatment of organ confined prostate cancer with third generation cryosurgery: preliminary multicenter experience. J Urol 2003; 170: 1126–1130.

    Article  Google Scholar 

  26. Bales GT et al. Short-term outcomes after cryosurgical ablation of the prostate in men with recurrent prostate carcinoma following radiation failure. Urology 1995; 46: 676–680.

    Article  CAS  Google Scholar 

  27. Pisters LL et al. The efficacy and complications of salvage cryotherapy of the prostate. J Urol 1997; 157: 921–925.

    Article  CAS  Google Scholar 

  28. Shinohara K, Carroll PR . Cryotherapy for prostate cancer. In: Walsh PC, Retik AB, Vaughan ED, Wein AJ (eds). Campbell's Urology, Vol 4. Saunders: Philadelphia, 2002, pp 3171–3181.

    Google Scholar 

  29. Katz AE, Ghafar MA . Selection of salvage cryotherapy patients. Rev Urol 2002; 4 (Suppl 2): S18–S23.

    PubMed  PubMed Central  Google Scholar 

  30. Donnely BJ, Saliken JC . Salvage cryosurgery-how I do it. Rev Urol 2002; 4 (Suppl 2): S24–S29.

    Google Scholar 

  31. Ghafar MA et al. Salvage cryotherapy using an argon based system for locally recurrent prostate cancer after radiation therapy: the Columbia experience. J Urol 2001; 166: 1333–1338.

    Article  CAS  Google Scholar 

  32. Benoit RM, Cohen JK, Miller RJ . Cryosurgery for prostate cancer: new technology and indications. Curr Urol Rep 2000; 1: 41–47.

    Article  CAS  Google Scholar 

  33. Chin JL et al. Results of salvage cryoablation of the prostate after radiation: identifying predictors of treatment failure and complications. J Urol 2001; 165: 1937–1941.

    Article  CAS  Google Scholar 

  34. Bahn DK et al. Salvage cryosurgery for recurrent prostate cancer after radiation therapy: a seven-year follow-up. Clin prostate cancer 2003; 2: 111–114.

    Article  Google Scholar 

  35. Link P, Freiha FS . Radical prostatectomy after definitive radiation therapy for prostate cancer. Urology 1991; 37: 189–192.

    Article  CAS  Google Scholar 

  36. Stein A, Smith RB, deKernion JB . Salvage radical prostatectomy after failure of curative radiotherapy for adenocarcinoma of the prostate. Urology 1992; 40: 197–200.

    Article  CAS  Google Scholar 

  37. Pontes JE, Montie J, Klein E, Huben R . Salvage surgery for radiation failure in prostate cancer. Cancer 1993; 71: 976–980.

    Article  CAS  Google Scholar 

  38. Brenner PC et al. Salvage radical prostatectomy in the management of locally recurrent prostate cancer after 125I implantation. Br J Urol 1994; 75: 44–47.

    Article  Google Scholar 

  39. Perrotte P et al. Quality of life after salvage cryotherapy: the impact of treatment paramenters. J Urol 1999; 162: 398–402.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. The Royal Surrey County Hospital, Egerton Road, Guildford, Surrey, UK

    S Ahmed, B Lindsey & J Davies

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  1. S Ahmed
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  2. B Lindsey
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  3. J Davies
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Correspondence to S Ahmed.

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Ahmed, S., Lindsey, B. & Davies, J. Salvage cryosurgery for locally recurrent prostate cancer following radiotherapy. Prostate Cancer Prostatic Dis 8, 31–35 (2005). https://doi.org/10.1038/sj.pcan.4500774

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