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Molecular biology

Hairpins at split ends in DNA

What do changing colours in corn kernels, mutations in houseflies and the variability of antibodies and of a T cell's antigen receptors in the vertebrate immune system have in common? A great deal, it turns out.

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Figure 1: Hairpin formation in transposition and V(D)J recombination.

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Oettinger, M. Hairpins at split ends in DNA. Nature 432, 960–961 (2004). https://doi.org/10.1038/432960b

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