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Sexual function in women with coronary artery disease: a preliminary study

Abstract

We investigated sexual function in female patients with coronary artery disease (CAD). A total of 20 consecutive female patients (38.2±3.8 years) with CAD diagnosed by coronary angiography and 15 healthy subjects (37.9±5.4 years) were enrolled in this study. The Female Sexual Function Index (FSFI) was used to assess sexual function in all the participants. Women with psychiatric disorders, gynecologic and systemic diseases that may affect sexual function were excluded from the study. The other exclusion criteria were usage of antidepressants and drugs affecting sexual function. Patients with CAD and healthy women were comparable in age, body mass index and education level. Female sexual dysfunction (FSD) was diagnosed in 12 of 20 women with CAD (60%), whereas five of 15 healthy women (33.3%) were found to have FSD (P<0.05). Patients with CAD had a significantly lower number of sexual intercourse episodes per month than healthy women volunteers (2.24 versus 5.2, respectively; P<0.05). The FSFI total score was clearly significantly decreased in the CAD group compared with that in healthy controls (17.8±2.9 and 26.0±4.8, P=0.001). When the subscores of each domain of FSFI were evaluated, all the subscores of FSFI, except the satisfaction domain, in patients with CAD were significantly lower than those of healthy subjects (P<0.05). This preliminary study demonstrates that female patients with CAD have distinct sexual dysfunction compared with healthy controls. Women with CAD should be evaluated also in terms of sexual function to provide better quality of life.

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References

  1. Kadri N, McHichi Alami KH, McHakra Tahiri S . Sexual dysfunction in women: population based epidemiological study. Arch Women Ment Health 2002; 5: 59.

    Article  CAS  Google Scholar 

  2. Laumann EO, Paik A, Rosen RC . Sexual dysfunction in the United States: prevalence and predictors. JAMA 1999; 10: 281–537.

    Google Scholar 

  3. Oberg K, Fugl-Meyer AR, Fugl-Meyer KS . On categorization and quantification of women's sexual dysfunctions: an epidemiological approach. Int J Impot Res 2004; 16: 261.

    Article  CAS  Google Scholar 

  4. Cayan S, Akbay E, Bozlu M, Canpolat B, Acar D, Ulusoy E . The prevalence of female sexual dysfunction and potential risk factors that may impair sexual function in Turkish women. Urol Int 2004; 72: 52.

    Article  Google Scholar 

  5. Chevret M, Jaudinot E, Sullivan K, Marrel A, De Gendre AS . Quality of sexual life and satisfaction in female partners of men with ED: psychometric validation of the Index of Sexual Life (ISL) questionnaire. J Sex Marital Ther 2004; 30: 141–155.

    Article  Google Scholar 

  6. Edwards WM, Coleman E . Defining sexual health: a descriptive overview. Arch Sex Behav 2004; 33: 189.

    Article  Google Scholar 

  7. Sullivan ME, Keoghane SR, Miller MA . Vascular risk factors and erectile dysfunction. BJU Int 2001; 87: 838–845.

    Article  CAS  Google Scholar 

  8. Montorsi F, Briganti A, Salonia A, Rigatti P, Margonato A, Macchi A et al. Erectile dysfunction prevalence, time of onset and association with risk factors in 300 consecutive patients with acute chest pain and angiographically documented coronary artery disease. Eur Urol 2003; 44: 360–364 (discussion 364–365).

    Article  Google Scholar 

  9. Kaya C, Uslu Z, Karaman MI . Is endothelial function impaired in erectile dysfunction patients? Int J Impot Res 2006; 18: 55–60.

    Article  CAS  Google Scholar 

  10. Kaiser DR, Billups K, Mason C, Wetterling R, Lundberg JL, Bank AJ . Impaired brachial artery endothelium-dependent and – independent vasodilation in men with erectile dysfunction and no other clinical cardiovascular disease. J Am Coll Cardiol 2004; 21: 179–184.

    Article  Google Scholar 

  11. Oksuz E, Malhan S . Prevalence and risk factors for female sexual dysfunction in Turkish women. J Urol 2006; 175: 654–658.

    Article  Google Scholar 

  12. Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R . The Female Sexual Function Index (FSFI): multidimensional self-report instruments for the assessment of female sexual function. J Sex Marital Ther 2000; 26: 191.

    Article  CAS  Google Scholar 

  13. Berman JR, Berman LA, Kym AK . Female sexual dysfunction: new perspectives on anatomy, physiology, evaluation and treatment. Eur Update Series 2003; 1: 166–177.

    Article  Google Scholar 

  14. Parazzini F, Menchini Fabris F, Bortolotti A, Calabro A, Chatenoud L, Colli E . Frequency and determinants of erectile dysfunction in Italy. Eur Urol 2000; 37: 43–49.

    Article  CAS  Google Scholar 

  15. Park K, Goldstein I, Andry C, Siroky MB, Krane RJ, Azadzoi KM . Vasculogenic female sexual dysfunction: the hemodynamic basis for vaginal engorgement insufficiency and clitoral erectile insufficiency. Int J Impot Res 1997; 9: 27.

    Article  CAS  Google Scholar 

  16. Kadioglu P, Yalin AS, Tiryakioglu O, Gaziolu N, Oral G, Sanli O et al. Sexual dysfunction in women with hyperprolactinemia: a pilot study report. J Urol 2005; 174: 1921–1925.

    Article  Google Scholar 

  17. Tessier DJ, Stone WM, Harold KL . Sexual function and quality of life in women after elective aortic surgery. Ann Vasc Surg 2004; 18: 428–432.

    Article  Google Scholar 

  18. Kostis JB, Jackson G, Rosen R, Barret-Connor E, Billups K, Burnett AL et al. Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Am J Cardiol 2005; 96: 313–321.

    Article  Google Scholar 

  19. Addis IB, Ireland CC, Vittinghoff E, Lin F, Stuenkel CA, Hulley S . Sexual activity and function in postmenopausal women with heart disease. Obstet Gynecol 2005; 106: 121–127.

    Article  Google Scholar 

  20. Rodriguez JJ, Al Dashti R, Schwarz ER . Linking erectile dysfunction and coronary artery disease. Int J Impot Res 2005; 17 (Suppl 1): S12–S18.

    Article  Google Scholar 

  21. Berman JR, Bassuk J . Physiology and pathophysiology of female sexual function and dysfunction. World J Urol 2002; 20: 111.

    Article  Google Scholar 

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Kaya, C., Yilmaz, G., Nurkalem, Z. et al. Sexual function in women with coronary artery disease: a preliminary study. Int J Impot Res 19, 326–329 (2007). https://doi.org/10.1038/sj.ijir.3901530

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  • DOI: https://doi.org/10.1038/sj.ijir.3901530

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