Nature 403, 614– 615 (2000)
To clarify possible misunderstanding over the term “new” in this communication, we meant our new model replaces the old Ogston model, as this is incompatible with our X-ray crystallographic data. We did not intend “new” in this context to mean that nobody had ever questioned the Ogston model before (for example, see refs 1–5).
References
Wilcox, P. E., Heidelberger, C. & Potter, V. R. Chemical preparation of asymmetrically labeled citric acid. J. Am. Chem. Soc. 72, 5019– 5024 (1950).
Bentley, R. Ogston and the development of the prochirality theory. Nature 276, 673–676 (1978).
Bentley, R. Three point attachment: past, present and no future. Ann. NY Acad. Sci. 41, 5–24 ( 1983).
Topiol, S. & Sabio, M. Interactions between eight centres are required for chiral recognition. J. Am. Chem. Soc. 111, 4109–4110 (1989).
Temussi, P. A. et al. Structure activity relationship of sweet molecules. Am. Chem. Soc. Symp. Ser. 450, 143– 161 (1990).
Additional information
Editorial note: As Brief Communications do not allow space for conventional introductions, we asked the authors for this addendum to clarify a possible misinterpretation.
Rights and permissions
About this article
Cite this article
Mesecar, A., Koshland, D. A new model for protein stereospecificity. Nature 408, 668 (2000). https://doi.org/10.1038/35047170
Issue Date:
DOI: https://doi.org/10.1038/35047170
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
