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Only one of two closely related yeast suppressor tRNA genes contains an intervening sequence

Nature volume 291, pages 464–469 (1981)Cite this article

Abstract

The yeast genes that code for the serine-inserting SUP-RL1 amber and SUQ5 ochre suppressors have been cloned and sequenced. These two unlinked genes differ by only three base pairs in their coding regions yet they encode tRNAs of different translational specificities, and while the SUP-RL1 gene has a 19-base pair intervening sequence, the SUQ5 gene has none.

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Author notes

  1. M. V. Olson: Department of Genetics, Box 8031, Washington University School of Medicine, St Louis, Missouri 63110, USA

  2. G. S. Page: Departments of Biochemistry and Biophysics, University of California, San Francisco, California 94113, USA

  3. A. Sentenac: Service Biochimie, Départment de Biologie, Centre d'Etudes Nucléaires de Saclay, BP No. 2, 91190, Gif-sur-Yvette, France

  4. P. W. Piper: Department of Biochemistry, University College London, Gower Street, London WC1E 6BT, UK

Authors and Affiliations

  1. Department of Genetics, University of Washington, Seattle, Washington, 98195, USA

    M. V. Olson, G. S. Page, A. Sentenac, P. W. Piper, M. Worthington, R. B. Weiss & B. D. Hall

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  1. M. V. Olson
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  2. G. S. Page
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  3. A. Sentenac
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  7. B. D. Hall
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Olson, M., Page, G., Sentenac, A. et al. Only one of two closely related yeast suppressor tRNA genes contains an intervening sequence. Nature 291, 464–469 (1981). https://doi.org/10.1038/291464a0

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