Abstract
Specific sites in supercoiled pVH51 and pBR322 DNAs are cleaved by single-strand specific nucleases. These sites are in the loops of potential cruciform structures.
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References
Gierer, A. Nature 212, 1480–1481 (1966).
Wells, R. D. et al. Prog. Nucleic Acid Res. molec. Biol. 24, 167–267 (1980).
Hsieh, T. & Wang, J. C. Biochemistry 14, 527–535 (1975).
Vologodskii, A. V., Lukashin, A. V., Anshelevich, V. V. & Frank-Kamenetskii, M. D. Nucleic Acids Res. 6, 967–982 (1979).
Wang, J. C. J. molec. Biol. 87, 797–816 (1974).
Vogt, V. Eur. J. Biochem. 33, 192–200 (1973).
Sadowski, P. D. J. biol Chem. 246, 209–216 (1971).
Center, M. S. & Richardson, C. C. J. biol. Chem. 245, 6285–6291 (1970).
Center, M. S., Studier, F. W. & Richardson, C. C. Proc. natn. Acad. Sci. U.S.A 65, 242–248 (1970).
Hardies, S. C. et al. J. biol Chem. 254, 5527–5534 (1979).
Oka, A. et al. Molec. gen. Genet. 172, 151–159 (1979).
Bartok, K. & Denhardt, D. T. J. biol Chem. 251, 530–535 (1976).
Beard, P., Morrow, J. F. & Berg, P. J. Virol. 12, 1303–1313 (1973).
Lau, P. P. & Gray, H. B. Nucleic Acids Res. 6, 331–357 (1979).
Baas, P. D., Teertstra, W. R. & Jansz, H. S. J. molec. Biol. 125, 167–185 (1978).
Sutcliffe, J. G. Cold Spring Harb. Symp. quant. Biol. 42, 77–90 (1978).
Scheffler, I. E., Elson, E. L. & Baldwin, R. L. J. molec. Biol. 48, 145–171 (1970).
Patient, R. K. et al. J. biol. Chem. 254, 5548–5554 (1979).
Funnell, B. E. & Inman, R. B. J. molec. Biol. 131, 331–340 (1979).
Reddy, V. B. et al. Science 200, 494–502 (1978).
Dodgson, J. B. & Wells, R. D. Biochemistry 16, 2374–2379 (1977).
Panayotatos, N. & Wells, R. D. J. biol. Chem. 254, 5555–5561 (1979).
Hershfield, V., Boyer, H. W., Chow, L. & Helinski, D. R. J. Bact. 126, 447–453 (1976).
Wells, R. D. et al. Meth. Enzym. 65, 327–347 (1980).
Panayotatos, N. & Wells, R. D. J. molec. Biol. 135, 91–109 (1979).
Panayotatos, N. & Wells, R. D. Nature 280, 35–39 (1979).
Maxam, A. M. & Gilbert, W. Proc. natn. Acad. Sci. U.S.A. 74, 560–564 (1977).
Godson, G. N., Barrell, B. G., Staden, R. & Fiddes, J. C. Nature 276, 236–247 (1978).
Sanger, F. et al. J. molec. Biol. 125, 225–246 (1978).
Beck, E. et al. Nucleic Acids Res. 5, 4495–4503 (1978).
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Panayotatos, N., Wells, R. Cruciform structures in supercoiled DNA. Nature 289, 466–470 (1981). https://doi.org/10.1038/289466a0
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DOI: https://doi.org/10.1038/289466a0
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