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Longevity and lifetime body weight in mice selected for rapid growth

Abstract

AN association between lifespan and early growth rate as affected by nutritional manipulation has been reported; high intake–rapid growth apparently contribute to shorter lifespan, and low intake–slow growth to longer lifespan1,2. Genetically determined rapid growth has also been reported to be associated with shortened lifespan3.

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References

  1. Berg, B. N., and Simms, H. S., J. Nutr., 71, 255–263 (1960).

    Article  CAS  Google Scholar 

  2. Ross, M. H., Lustbader, E., and Bras, G., Nature, 250, 548–553 (1976).

    Article  ADS  Google Scholar 

  3. Roberts, R. C., Heredity, 16, 369–381 (1961).

    Article  Google Scholar 

  4. Bradford, G. E., Genetics, 69, 499–512 (1971).

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Robinson, D. W., and Bradford, G. E., Growth, 33, 221–230 (1969).

    CAS  PubMed  Google Scholar 

  6. Mears, G. J., and Mendel, V. E., J. Physiol., Lond., 240, 609–624 (1974).

    Article  CAS  Google Scholar 

  7. Meyer, H. H., and Bradford, G. E., J. Anim. Sci., 38, 271–278 (1974).

    Article  CAS  Google Scholar 

  8. Robinson, D. W., Hodgson, D., Bradford, G. E., Robb, J., and Peterson, D. W., J. Anim. Sci., 40, 1058–1062 (1975).

    Article  CAS  Google Scholar 

  9. Ross, M. H., and Bras, G., J. Nutr., 87, 245–260 (1965).

    Article  CAS  Google Scholar 

  10. Drori, D., and Folman, Y., Expl Geront., 4, 263–266 (1969).

    Article  CAS  Google Scholar 

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EKLUND, J., BRADFORD, G. Longevity and lifetime body weight in mice selected for rapid growth. Nature 265, 48–49 (1977). https://doi.org/10.1038/265048b0

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  • DOI: https://doi.org/10.1038/265048b0

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