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Products of the major histocompatibility complex and their relationship to the immune response

Nature volume 264, pages 145–152 (1976)Cite this article

Abstract

The genes of the major histocompatibility complex were first known for the part they played in transplant rejection. Recently, however, it has become clear that the products of that region have an important part to play in the control of the immune response, through their effects both on cooperative and on aggressive interactions between cells. It is now possible to guess at the mechanisms which may underly the association of some major histocompatibility antigens with disease.

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  1. Immunology Division, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, UK

    Alan Munro & Susan Bright

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Munro, A., Bright, S. Products of the major histocompatibility complex and their relationship to the immune response. Nature 264, 145–152 (1976). https://doi.org/10.1038/264145a0

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