Abstract
1975 is the fiftieth anniversary of the proposal, by Gorter and Grendel, that biological membranes are based on a lipid bilayer. Now well established, this proposal, like the DNA double helix, was a major breakthrough in molecular cell biology. Here we discuss current concepts about the molecular composition, organisation and behaviour of the plasma membranes of mammalian erythrocytes and nucleated cells.
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Bretscher, M., Raff, M. Mammalian plasma membranes. Nature 258, 43–49 (1975). https://doi.org/10.1038/258043a0
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DOI: https://doi.org/10.1038/258043a0
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