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Transplantation and preliminary characterisation of lymphocyte surface markers of Abelson virus-induced lymphomas

Abstract

MOST murine lymphomas induced by commonly available murine leukaemia viruses (such as Gross passage A and Moloney leukaemia viruses) arise in the thymus1, originating as thymocytes or thymus-derived (T) cells. The tumours thus usually carry the surface θ antigen2, they rarely have B-cell surface markers such as the κ (light) chain. Abelson and Rabstein, however, reported a leukaemia virus that induces non-thymic lymphomas3–5, which we have now found to have surface κ chains under certain circumstances.

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SKLAR, M., SHEVACH, E., GREEN, I. et al. Transplantation and preliminary characterisation of lymphocyte surface markers of Abelson virus-induced lymphomas. Nature 253, 550–552 (1975). https://doi.org/10.1038/253550a0

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