Abstract
MOST murine lymphomas induced by commonly available murine leukaemia viruses (such as Gross passage A and Moloney leukaemia viruses) arise in the thymus1, originating as thymocytes or thymus-derived (T) cells. The tumours thus usually carry the surface θ antigen2, they rarely have B-cell surface markers such as the κ (light) chain. Abelson and Rabstein, however, reported a leukaemia virus that induces non-thymic lymphomas3–5, which we have now found to have surface κ chains under certain circumstances.
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References
Gross, L., Oncogenic viruses, 286 (Pergamon, New York, 1970).
Shevach, E. M., Stobo, J. D., and Green, I., J. Immunol., 108, 1146 (1972).
Abelson, H. T., and Rabstein, L. S., Cancer Res., 30, 2213 (1970).
Rabstein, L. S., Gazdar, A. F., Chopra, H. C., and Abelson, H. T., J. natn. Cancer Inst., 46, 481 (1971).
Siegler, R., Zajdel, S., and Lane, I., J. natn. Cancer Inst., 48, 189 (1972).
Potter, M., Pumphrey, J., and Walters, J., J. natn. Cancer Inst., 49, 305 (1972).
Rowe, W. P., Pugh, W. E., and Hartley, J. W., Virology, 42, 1136 (1970).
Potter, M., Sklar, M. D., Rowe, W. P., Science, 182, 592 (1973).
Wood, B. T., Thompson, S. H., and Goldstein, G., J. Immunol., 95, 275 (1965).
Reiff, A. E., and Allen, J. M., J. exp. Med., 120, 413 (1964).
Shevach, E. M., Jaffe, E. S., and Green, I., Transplant. Rev., 16, 3 (1973).
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SKLAR, M., SHEVACH, E., GREEN, I. et al. Transplantation and preliminary characterisation of lymphocyte surface markers of Abelson virus-induced lymphomas. Nature 253, 550–552 (1975). https://doi.org/10.1038/253550a0
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DOI: https://doi.org/10.1038/253550a0
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