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Antibody activity associated with immunoglobulins synthesised by human lymphoblastoid cell lines

Abstract

ANTIBODY activity has not previously been detected in association with immunoglobulins synthesised spontaneously by human lymphoblastoid cell lines in vitro. One reviewer has commented “if some antibody activity was to be found, the established cell lines would be a fascinating tool for the study of homogenous antibodies”1. We here report such a finding.

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STEEL, C., EVANS, J., JOSS, A. et al. Antibody activity associated with immunoglobulins synthesised by human lymphoblastoid cell lines. Nature 252, 604–605 (1974). https://doi.org/10.1038/252604a0

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