Abstract
IN this report we examine the behaviour of mouse thymocytes in the mixed lymphocyte culture. The thymus is believed to contain large numbers of T cell precursors or immature T cells undergoing differentiation before migrating to the peripheral lymphoid areas as mature, immunocompetent cells. Our results suggest that the thymus contains a class of cell possessing the potential to react against products of H-2 and non-H-2 loci, but that mixed leukocyte culture reactivity against H-2 depends on a factor(s) present in normal mouse serum.
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PECK, A., BACH, F. Differential recognition by thymocytes of H-2 and non-H-2 alloantigens. Nature 252, 507–508 (1974). https://doi.org/10.1038/252507a0
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DOI: https://doi.org/10.1038/252507a0
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