Abstract
IN spite of the well documented effect of early undernutrition on body and brain size in adult animals1–3, its reported influence on behaviour has been less consistent. Changes in performance in learning tasks and activity tests have been found following undernutrition in early life4–7. Several studies, however, have shown little or no effect of such a manipulation8–10. Here we consider two factors which may contribute to variability in later behavioural response to early life undernutrition.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Winick, M., and Noble, A., J. Nutr., 89, 300–306 (1966).
Winick, M., Rosso, P., and Brasel, J. A., in Lipids, Malnutrition and the Developing Brain, 199–206 (Elsevier, New York, 1972).
Barnes, R. H., Cunnold, S. R., Zimmerman, R. R., Simmons, H., Macleod, R. B., and Krook, L., J. Nutr., 89, 399–410 (1966).
Barnes, R. H., Neely, C. S., Kwong, E., Labadan, B. A., and Frankova, S., J. Nutr., 96, 467–476 (1968).
Levitsky, D. A., and Barnes, R. H., Nature, 225, 468–469 (1970).
Dobbing, J., and Smart, J. L., in Ethology and Development, (edit. by Barnett, S. A.), 16–36 (Lippincott, Philadelphia, 1973).
Slob, A. K., thesis (University of Rotterdam, 1973).
Guthrie, H. A., Physiol. Behav., 3, 619–623 (1968).
Ali Rajalakshmi, R. S. Z., and Ramakrishnan, C. V., J. Neurochem., 14, 506–509 (1967).
Stein, Z., Susser, M., Saenger, G., and Marolla, F., Science, 178, 708–713 (1972).
Frankova, S., in Malnutrition, Learning and Behaviour (edit. by Scrimshaw, N. S. and Gordon, J. E.), 312–322 (Cambridge, MIT Press, 1968).
Frankova, S., Proc. 8th Congr. Nutr., Excerpta. Medica Int. Cong. Ser., 213, 236–239 (1970).
Levitsky, D. A., and Barnes, R. H., Science, 176, 68–71 (1971).
Biology of the Laboratory Mouse, 2nd ed. (edit. by Green, E. I.) (McGraw Hill, New York, 1966).
Winer, B. J., Statistical Principles in Experimental Design, 202, (McGraw-Hill, New York, 1962).
Henderson, N. D., Anim. Behav., 15, 364–376 (1967).
Erlenmeyer-Kimling, L., in Genetics, Environment and Behaviour (edit. by Ehrman, L.), 181 (Academic Press, New York, 1972).
Manosewitz, M., and McCanne, T. R., J. comp. physiol. Psychol., 83, 2, 314–323 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BLIZARD, D., RANDT, C. Genotype interaction with undernutrition and external environment in early life. Nature 251, 705–707 (1974). https://doi.org/10.1038/251705a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/251705a0
This article is cited by
-
Use of A Standard Strain for External Calibration in Behavioral Phenotyping
Behavior Genetics (2005)
-
The influence of early nutrition and environmental rearing on brain growth and behaviour
Experientia (1976)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.