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The neurogenic and myogenic hypotheses in human (Duchenne) muscular dystrophy

A Corrigendum to this article was published on 14 June 1974

Abstract

X-LINKED recessive (Duchenne) muscular dystrophy (DMD) is the most common, consistent, and disastrous form of the diseases in man. Evidence that it is neurogenic1 is open to criticism2,3. Though an apparently similar condition in mice, often used as a model, may be neurogenic4, its different serology5 and mode of inheritance6 suggest a fundamental dissimilarity. The following observations on the human disease bring new evidence to bear on the issue.

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THOMSON, W., SWEETIN, J. & ELTON, R. The neurogenic and myogenic hypotheses in human (Duchenne) muscular dystrophy. Nature 249, 151–152 (1974). https://doi.org/10.1038/249151a0

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