This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Romana SP, Mauchauffe M, Le Coniat M, Chumakov I, Le Paslier D, Berger R et al. The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion. Blood 1995; 85: 3662–3670.
Golub TR, Barker GF, Bohlander SK, Hiebert SW, Ward DC, Bray-Ward P et al. Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. Proc Natl Acad Sci USA 1995; 92: 4917–4921.
Ford AM, Bennett CA, Price CM, Bruin MC, Van Wering ER, Greaves M . Fetal origins of the TEL-AML1 fusion gene in identical twins with leukemia. Proc Natl Acad Sci USA 1998; 95: 4584–4588.
Wiemels JL, Ford AM, Van Wering ER, Postma A, Greaves M . Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. Blood 1999; 94: 1057–1062.
Ford AM, Fasching K, Panzer-Grumayer ER, Koenig M, Haas OA, Greaves MF . Origins of ‘late’ relapse in childhood acute lymphoblastic leukemia with TEL-AML1 fusion genes. Blood 2001; 98: 558–564.
Konrad M, Metzler M, Panzer S, Ostreicher I, Peham M, Repp R et al. Late relapses evolve from slow-responding subclones in t(12;21)-positive acute lymphoblastic leukemia: evidence for the persistence of a preleukemic clone. Blood 2003; 101: 3635–3640.
Attarbaschi A, Mann G, Konig M, Dworzak MN, Trebo MM, Muhlegger N et al. Austrian Berlin–Frankfurt–Munster cooperative study group. Incidence and relevance of secondary chromosome abnormalities in childhood TEL/AML1+ acute lymphoblastic leukemia: an interphase FISH analysis. Leukemia 2004; 18: 1611–1616.
Taketani T, Taki T, Sugita K, Furuichi Y, Ishii E, Hanada R et al. FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy. Blood 2004; 103: 1085–1088.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Inukai, T., Yokota, S., Okamoto, T. et al. Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse. Leukemia 20, 363–365 (2006). https://doi.org/10.1038/sj.leu.2404077
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.leu.2404077
This article is cited by
-
Outcome of pediatric acute lymphoblastic leukemia with very late relapse: a retrospective analysis by the Tokyo Children’s Cancer Study Group (TCCSG)
International Journal of Hematology (2015)
-
Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia
Leukemia (2008)