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Acute myelogenous leukemia in Chile PINDA protocols 87 and 92 results

Leukemia volume 19, pages 2143–2146 (2005)Cite this article

TO THE EDITOR

Acute myelogenous leukemia (AML) remains a challenging disease. Although responsible for only 15–20% of childhood leukemias, it amounts to up to a 30% of all leukemia-related deaths.1 Over the last three decades, there has been significant progress in the treatment of this disease, mostly due to the introduction of multiple drug regimens, treatment intensification, and improvements in postremission therapy. Early mortality has been addressed by a number of authors, since it is responsible for a significant proportion of all AML deaths.1, 2, 3, 4, 5, 6, 7 In general, it is said that approximately half of early deaths are due to treatment toxicity.1 In developing countries, such as Chile, treatment toxicity may be even higher, mostly from infectious complications.

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Authors and Affiliations

  1. Hospital Luis Calvo Mackenna, Oncology Unit Santiago, Chile

    J Quintana & V Beresi

  2. Hospital Clínico San Borja Arriarán, Oncology Unit, Santiago, Chile

    P Advis

  3. Hospital Sótero del Río, Pediatric Oncology Unit, Santiago, Chile

    A Becker

  4. Hospital Roberto del Río, Pediatric Oncology Unit, Santiago, Chile

    M Campbell

  5. Radiotherapy Department, Clínica Santa María, Chile

    E F Vinés

  6. Hospital San Juan de Dios, Pediatric Oncology Unit, Santiago, Chile

    H García & L Vargas

  7. Hospital Exequiel González Cortés, Pediatric Oncology Unit, Santiago, Chile

    C Salgado

  8. Hospital Guillermo Grant Benavente, Pediatric Oncology Unit, Concepción, Chile

    J Rojas

  9. Hospital Higueras, Talcahuano, Pediatric Oncology Unit, Chile

    M Obando

  10. Hospital Gustavo Fricke, Pediatric Oncology Unit, Viña del Mar, Chile

    L Neira

  11. Hospital Regional de Temuco, Pediatric Oncology Unit, Chile

    E Páez

  12. Hospital Regional de Valdivia, Pediatric Oncology Unit, Chile

    P Zolezzi

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  1. J Quintana
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  2. P Advis
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  14. P Zolezzi
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Consortia

for the Programa Infantil de Drogas Antineoplásicas de Chile (PINDA)

Corresponding author

Correspondence to J Quintana.

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Quintana, J., Advis, P., Becker, A. et al. Acute myelogenous leukemia in Chile PINDA protocols 87 and 92 results. Leukemia 19, 2143–2146 (2005). https://doi.org/10.1038/sj.leu.2403959

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  • DOI: https://doi.org/10.1038/sj.leu.2403959

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