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References
Freedman MH, Bonilla MA, Fier C, Bolyard AA, Scarlata D, Boxer LA et al. Myelodysplasia syndrome and acute myeloid leukemia in patients with congenital neutropenia receiving G-CSF therapy. Blood 2000; 96: 429–436.
Dong F, Dale DC, Bonilla MA, Freedman M, Fasth A, Neijens HJ et al. Mutations in the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia. Leukemia 1997; 11: 120–125.
Tidow N, Pilz C, Teichmann B, Muller-Brechlin A, Germeshausen M, Kasper B et al. Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia. Blood 1997; 89: 2369–2375.
Avalos BR . Molecular analysis of the granulocyte colony-stimulating factor receptor. Review. Blood 1996; 88: 761–777.
Dong F, Brynes RK, Tidow N, Welte K, Lowenberg B, Touw IP . Mutations in the gene for the granulocyte colony-stimulating factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia. N Engl J Med 1995; 333: 487–493.
Morikawa K, Morikawa S, Nakamura M, Miyawaki T . Characterization of granulocyte colony-stimulating factor receptor expressed on human lymphocytes. Br J Haematol 2002; 118: 296–304.
Inukai T, Sugita K, Iijima K, Goi K, Tezuka T, Kojika S et al. Leukemic cells with 11q23 translocations express granulocyte colony-stimulating factor (G-CSF) receptor and their proliferation is stimulated with G-CSF. Leukemia 1998; 12: 382–389.
Germeshausen M, Ballmaier M, Schulze H, Welte K, Flohr T, Beiske K et al. Granulocyte colony-stimulating factor receptor mutations in a patient with acute lymphoblastic leukemia secondary to severe congenital neutropenia. Blood 2001; 97: 829–830.
Bernard T, Gale RE, Evans JP, Linch DC . Mutations of the granulocyte-colony stimulating factor receptor in patients with severe congenital neutropenia are not required for transformation to acute myeloid leukaemia and may be a bystander phenomenon. Br J Haematol 1998; 101: 141–149.
Hermans MH, van de Geijn GJ, Antonissen C, Gits J, van Leeuwen D, Ward AC et al. Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells. Blood 2003; 101: 2584–2590.
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This work has been supported by grants from the Association pour le Recherche contre le Cancer, and from AFM-Inserm network.
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Cassinat, B., Bellanné-Chantelot, C., Notz-Carrère, A. et al. Screening for G-CSF receptor mutations in patients with secondary myeloid or lymphoid transformation of severe congenital neutropenia. A report from the French neutropenia register. Leukemia 18, 1553–1555 (2004). https://doi.org/10.1038/sj.leu.2403431
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DOI: https://doi.org/10.1038/sj.leu.2403431
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