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EBV-related lymphoproliferative disorders in immunocompetent patients

Leukemia volume 17, pages 2537–2538 (2003)Cite this article

TO THE EDITOR

The new WHO classification of lymphomas recognizes four clinical settings of immunodeficiency associated with an increased incidence of lymphoma and other lymphoproliferative disorders: (1) primary immune disorders; (2) HIV infection; (3) iatrogenic immunosuppression after solid organ or bone marrow transplantation; and (4) iatrogenic immunosuppression due to methotrexate treatment.1 We describe three patients with an EBV-related lymphoproliferative disorder (LPD) without known underlying primary or secondary immune disorder, and suggest that EBV-related LPDs may occur more frequently than expected.

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Figure 1

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Author notes

  1. M Oosterveld and W J Lesterhuis: Both authors contributed equally to this report.

Authors and Affiliations

  1. Department of Hematology, University Medical Centre Nijmegen, The Netherlands

    M Oosterveld & M MacKenzie

  2. General Internal Medicine, University Medical Centre Nijmegen, The Netherlands

    W J Lesterhuis

  3. Pathology, University Medical Centre Nijmegen, The Netherlands

    J H J M van Krieken

Authors
  1. M Oosterveld
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  2. W J Lesterhuis
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  3. M MacKenzie
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  4. J H J M van Krieken
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Oosterveld, M., Lesterhuis, W., MacKenzie, M. et al. EBV-related lymphoproliferative disorders in immunocompetent patients. Leukemia 17, 2537–2538 (2003). https://doi.org/10.1038/sj.leu.2403155

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  • DOI: https://doi.org/10.1038/sj.leu.2403155

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