This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Hunger SP . Chromosomal translocations involving the E2A gene in acute lymphoblastic leukemia; clinical features and molecular pathogenesis Blood 1996 87: 1211–1224
Inaba T, Inukai T, Yoshihara T, Seyschab H, Ashmun RA, Canman CE, Laken SJ, Kastan MB, Look AT . Reversal of apoptosis by the leukemia-associated E2A-HLF chimeric transcriptional factor Nature 1996 382: 541–544
Altura RA, Inukai T, Ashmun RA, Zambetti GP, Roussel MF, Look AT . The chimeric E2A-HLF transcription factor abrogates p53-induced apoptosis in myeloid leukemia cells Blood 1998 92: 1397–1045
Devaraj PE, Foroni L, Sekhar M, Butler T, Wright L, MehtaA, Samson D, Prentice HG, Hoffbrand AV, Secker-Walker LM . E2A/HLF fusion cDNAs and the use of RT-PCR for the detection of minimal residual disease in t(17;19)(q22;p13) acute lymphoblastic leukemia Leukemia 1994 8: 1131–1138
Hunger SP, Devaraj PE, Foroni L, Secker-Walker LM, Cleary ML . Two types of genomic rearrangement create alternative E2A-HLF fusion proteins in t(17;19)-ALL Blood 1994 83: 2970–2977
Hunger SP, Brown R, Cleary ML . DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF Mol Cell Biol 1994 14: 5986–5996
Ohyashiki K, Fujieda H, Miyauchi J, Ohyashiki JH, Tauchi T, Saito M, Nakazawa S, Abe K, Yamamoto K, Clark SC, Toyama K . Establishment of a novel heterotransplantable acute lymphoblastic leukemia cell line with a t(17;19) chromosomal translocation, the growth of which is inhibited by interleukin-3 Leukemia 1991 5: 322–331
Zhang LQ, Downie PA, Goodell WR, McCabe NR, LeBeau MM, Morgan R, Sklar J, Raimondi SC, Miley D, Goldberg A, Lu MM, Montag A, Smith SD . Establishment of cell lines from B-cell precursor acute lymphoblastic leukemia Leukemia 1993 7: 1865–1874
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Takahashi, H., Goto, H., Funabiki, T. et al. Expression of two types of E2A-HLF fusion proteins in YCUB-2, a novel cell line established from B-lineage leukemia with t(17;19). Leukemia 15, 995–997 (2001). https://doi.org/10.1038/sj.leu.2402120
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.leu.2402120
This article is cited by
-
Molecular analysis of more than 140 gene fusion variants and aberrant activation of EVI1 and TLX1 in hematological malignancies
Annals of Hematology (2017)
-
The E2A-HLF oncogenic fusion protein acts through Lmo2 and Bcl-2 to immortalize hematopoietic progenitors
Leukemia (2011)
-
Hypercalcemia in childhood acute lymphoblastic leukemia: frequent implication of parathyroid hormone-related peptide and E2A-HLF from translocation 17;19
Leukemia (2007)
-
N-(4-Hydroxyphenyl)retinamide (4-HPR) Induces Leukemia Cell Death via Generation of Reactive Oxygen Species
International Journal of Hematology (2003)