This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
A rare BCR-ABL1 transcript in Philadelphia-positive acute myeloid leukemia: case report and literature review
BMC Cancer Open Access 10 January 2019
-
Philadelphia chromosome positive AML arising from JAK2-positive myelofibrosis
Biomarker Research Open Access 21 November 2018
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Melo JV . The molecular biology of chronic myeloid leukemia Leukemia 1996 10: 751–756
Saglio G, Guerrasio A, Rosso C, Tassinari A, Serra A, Rege-Cambrin G, Mazza U, Gavosto F . New type of BCR/ABL junction in Philadelphia chromosome-positive chronic myelogenous leukemia Blood 1990 76: 1819–1824
Chiesa J, Bureau JP . In situ Hybridization on chromosomes: clinical applications. In: Morel G (ed) Visualisation of Nucleic Acids CRC Press: Boca Raton, FL 1995 pp 185–199
Chomczynski P, Sacchi N . Single-step method of RNA isolation by acid guanidinium thiocyanate–phenol–chloroform extraction Anal Biochem 1987 162: 156–159
Melo JV, Kent NS, Yan XH, Goldman JM . Controls for reverse transcriptase-polymerase chain reaction amplification of BCR-ABL transcripts Blood 1994 84: 3984–3986
Van Dongen JJM, Macintyre EA, Gabert JA, Delabesse E, Rossi V, Saglio G, Gottardi E, Rambaldi A, Dotti G, Griesinger F, Parreira A, Gameiro P, Gonzalez Diaz M, Malec M, Langerak AW, San Miguel JF, Biondi A . Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease Leukemia 1999 13: 1901–1928
Rey JM, Pujol P, Callier P, Cavailles V, Freiss G, Maudelonde T, Brouillet JP . Semiquantitative reverse transcription-polymerase chain reaction to evaluate the expression patterns of genes involved in the oestrogen pathway J Mol Endocrinol 2000 24: 433–440
Cross NCP, Melo JV, Feng L, Goldman JM . An optimized multiplex polymerase chain reaction (PCR) for detection of BCR-ABL fusion mRNAs in haematoligical disorders Leukemia 1994 8: 186–189
Hochhaus A, Reiter A, Skladny H, Melo JV, Sick C, Berger U, Guo JQ, Arhlingaus RB, Hehlmann R, Goldman JM, Cross NCP . A novel BCR-ABL fusion gene (e6a2) in a patient with Philadelphia chromosome-negative chronic myelogenous leukemia Blood 1996 88: 2236–2240
Acknowledgements
This work was support by the Regional Hospital Center of Montpellier. We thank Dr Jean Marc Rey for sequencing, Mireille Audema and Line Lioure for technical assistance, Dr Isabelle Touitou for sientific advice and Andrew Goldsborough for manuscript comments.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Dupont, M., Jourdan, E. & Chiesa, J. Identification of E6A2 BCR-ABL fusion in a Philadelphia-positive CML. Leukemia 14, 2011–2012 (2000). https://doi.org/10.1038/sj.leu.2401916
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.leu.2401916
This article is cited by
-
A rare BCR-ABL1 transcript in Philadelphia-positive acute myeloid leukemia: case report and literature review
BMC Cancer (2019)
-
Philadelphia chromosome positive AML arising from JAK2-positive myelofibrosis
Biomarker Research (2018)
-
BCR–ABL1 e6a2 transcript in chronic myeloid leukemia: biological features and molecular monitoring by droplet digital PCR
Virchows Archiv (2015)
-
CML with e6a2 BCR-ABL1 transcript: an aggressive entity?
Annals of Hematology (2011)
-
Successful treatment of imatinib-resistant acute megakaryoblastic leukemia with e6a2 BCR/ABL: use of dasatinib and reduced-conditioning stem-cell transplantation
Leukemia (2007)