Abstract
EVIDENCE for the existence of two non-allelic Hba structural loci in the domestic goat has been presented1,2. The products of these loci, termed Iα and IIα chains3, differ in at least four positions. Glycine, alanine, leucine and asparagine occupy positions 19, 26, 113 and 115 in the Iα chain, respectively, whereas serine, threonine, histidine and serine are present in these positions of the IIα chain2. The percentages of Iα and IIα chains in red cell haemolysates of normal AA goats are about 72 and 28, indicating that evolution of the duplicated Hba loci is associated with a three-fold decrease (or increase) in Hba locus efficiency3. No such α chain multiplicity was observed in the domestic sheep4.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Huisman, T. H. J., Wilson, J. B., and Adams, H. R., Arch. Biochem. Biophys., 121, 529 (1967).
Huisman, T. H. J., Brandt, G., and Wilson, J. B., J. Biol. Chem., 243, 3675 (1968).
Adams, H. R., Wrightstone, R. N., Miller, A., and Huisman, T. H. J., Arch. Biochem. Biophys., 132, 223 (1969).
Wilson, J. B., Brandt, G., and Huisman, T. H. J., J. Biol. Chem., 243, 3687 (1968).
Huisman, T. H. J., van Vliet, G., and Sebens, T., Nature, 182, 171 (1958).
Meyer, H., Z. Säugetierk., 32, 178 (1967).
Huisman, T. H. J., Dasher, G. A., Moretz, jun., W. H., Dozy, A. M., Wilson, J. B., and van Vliet, G., Biochem. J., 107, 745 (1968).
Payne, S., Proc. Prehistoric Soc., 34, 368 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WILSON, J., WRIGHTSTONE, R. & HUISMAN, T. Haemoglobin α Chain Duplication in Barbary Sheep, Ammotragus lervia, Pallas, 1777. Nature 226, 354–355 (1970). https://doi.org/10.1038/226354a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/226354a0
This article is cited by
-
Structure and organization of Caprinae globin genes
Zeitschrift für Jagdwissenschaft (2002)
-
Hemoglobin types in saanen goats and Barbary sheep: Genetic and comparative aspects
Biochemical Genetics (1988)
-
Hemoglobin types in saanen goats and Barbary sheep: Genetic and comparative aspects
Biochemical Genetics (1988)
-
Evolutionary trends in the hemoglobins of murine animals
Journal of Biosciences (1980)
-
Gene diversity of bovid hemoglobins
Biochemical Genetics (1978)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.