Abstract
Macdonald and Ellis report1 that cycloheximide inhibits the uptake of chloride in storage tissue disks of beet, carrot and potato, and in roots of wheat and pea plants. It was also found that oxygen uptake was markedly stimulated by the antibiotic in beet and carrot disks, slightly stimulated in potato disks, and not affected in wheat or pea roots. These findings were considered to suggest that cycloheximide can disrupt cellular metabolism in other ways than the inhibition of protein synthesis.
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KIRK, J. Failure to detect Effects of Cycloheximide on Energy Metabolism in Euglena gracilis. Nature 226, 182 (1970). https://doi.org/10.1038/226182a0
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DOI: https://doi.org/10.1038/226182a0
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