Abstract
An electron density map has been calculated at a resolution of 2.8 Å which shows many details of the arrangement of the atoms in rhombohedral crystals of insulin.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Ryle, A. P., Sanger, F., Smith, L. F., and Kitai, R., Biochem. J., 60, 541 (1955).
Abel, J. J., Proc. US Nat. Acad. Sci., 12, 132 (1926).
Crowfoot, D. M., Nature, 135, 591 (1935).
Harding, M. M., Hodgkin, D. C., Kennedy, A. F., O'Connor, A., and Weitzmann, P. D. J., J. Mol. Biol., 16, 212 (1966).
Dodson, E. J., Harding, M. M., Hodgkin, D. C., and Rossmann, M. G., J. Mol. Biol., 16, 227 (1966); Low, E. W., and Einstein, J. R., Nature, 186, 470 (1960).
Schlichtkrull, J., Acta Chem. Scand., 10, 1455 (1956); thesis, Copenhagen University (1958).
Singh, A. K., and Ramaseshan, S., Acta Cryst., 21, 279 (1966).
Kung et al., Scientia Sinica, 15, 544 (1966).
Katsoyannis, P. G., and Tometsko, A., Proc. US Nat. Acad. Sci., 65, 1554 (1966).
Zahn, H., et al., Z. Naturforsch., 20B, 666 (1965); Liebig Ann. d'Chem., 691, 225 (1966).
Carpenter, F. H., Amer. J. Med., 40, 750 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ADAMS, M., BLUNDELL, T., DODSON, E. et al. Structure of Rhombohedral 2 Zinc Insulin Crystals. Nature 224, 491–495 (1969). https://doi.org/10.1038/224491a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/224491a0
This article is cited by
-
Insulin investigations
Nature Chemistry (2023)
-
Living in Sweet Sorrow: Diabetes Mellitus in India
Journal of the Indian Institute of Science (2023)
-
100 years of insulin: celebrating the past, present and future of diabetes therapy
Nature Medicine (2021)
-
Amyloid formation of bovine insulin is retarded in moderately acidic pH and by addition of short-chain alcohols
European Biophysics Journal (2020)
-
Insulin and its receptor: a grand challenge in structural biology
Biophysical Reviews (2019)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.