Abstract
Malignancy can be suppressed when malignant cells are fused with certain non-malignant ones. The hybrid cells derived from such fusions give rise to segregants in which a loss of chromosomes is associated with reversion to malignancy. The expression of histo-compatibility antigens can also be suppressed when cells bearing these antigens are fused with others that express them poorly.
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HARRIS, H., MILLER, O., KLEIN, G. et al. Suppression of Malignancy by Cell Fusion. Nature 223, 363–368 (1969). https://doi.org/10.1038/223363a0
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DOI: https://doi.org/10.1038/223363a0
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