Abstract
FOR the elucidation of paths of both migration and evolution, proteins offer certain advantages over other biological markers: qualitative alterations of proteins are usually transmitted in specific genetic patterns; each multicellular form of life has many proteins; and each protein is susceptible to genetic modification in many different ways. The last two features suggest that enough protein markers are potentially available to render unlikely the possibility that two species or geographic isolates are similar by chance alone. Among genetic markers in man, variants of red cell glucose-6-phosphate dehydrogenase (G-6-PD) have begun to show sufficient ethnic and geographic specificity to justify their inclusion in the list of such protein markers.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Yoshida, A., Proc. US Nat. Acad. Sci., 57, 835 (1967).
Scientific Group, WHO Tech. Rep. Ser., No. 366 (1967).
Azevedo, E., Kirkman, H. N., Morrow, A. C., and Motulsky, A. G., Ann. Hum. Genet., 31, 373 (1968).
Kirkman, H. N., Kidson, C., and Kennedy, M., Hereditary Disorders of Erythrocyte Metabolism (edit. by Beutler, E.), 126 (Grune and Stratton, New York, 1968).
Wilkinson, G. N., Biochem. J., 80, 324 (1961).
Kirkman, H. N., Schettini, F., and Pickard, B. M., J. Lab. Clin. Med., 63, 726 (1964).
Fernandez, M. N., and Fairbanks, V. F., Mayo Clinic Proc., 43, 645 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KIRKMAN, H., ENG, LI. Variants of Glucose-6-phosphate Dehydrogenase in Indonesia. Nature 221, 959–960 (1969). https://doi.org/10.1038/221959a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/221959a0
This article is cited by
-
Biochemical characteristics of glucose-6-phosphate dehydrogenase variants among the Malays of Singapore with report of a new non-deficient (Gd Singapore) and three deficient variants
Japanese Journal of Human Genetics (1991)
-
Glucose-6-phosphate dehydrogenase (G6PD) iserlohn and G6PD regensburg: Two new severe enzyme defects in german families
Blut (1985)
-
Glucose 6-phosphate dehydrogenase variants of Bali Island (Indonesia)
Human Genetics (1982)
-
Biochemische Eigenschaften einer neuen Variante des Glucose-6-phosphatdehydrogenase (G-6-PD)-Mangels mit Favismus: G-6-PD Bielefeld
Klinische Wochenschrift (1977)
-
Three glucose 6-phosphate dehydrogenase variants found in Japan
Human Genetics (1977)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
