Abstract
ALTHOUGH the bone marrow cell population is known to affect both the structure and function of thymus tissue1, experimental data indicating any defined influence of the thymus on bone marrow anatomy or physiology are scanty and inconclusive2. Thymectomy performed in Wistar rats a few weeks after birth does not modify their bone marrow cell population3. Thymectomy within 48 h of birth seems to produce an increase in the number of blasts (stem cells) and immature erythroblasts normally present in this tissue, however4. An increased percentage of immature erythroblasts in the bone marrow of thymectomized embryos has also been described in the opossum5.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kaplan, H. S., Brown, M. B., and Paull, J., J. Nat. Cancer Inst., 14, 303 (1953); Gengozian, N., Urso, I. S., Congdon, C. C., Conger, A. D., and Makinodan, T., Proc. Soc. Exp. Biol. and Med., 96, 714 (1957); Ford, C. E., and Micklem, H. S., Lancet, i, 359 (1963).
Miller, J. F. A. P., and Howard, J. C., J. Reticuloendothelial Soc., 1, 369 (1964).
Bierring, F., in Ciba Found. Symp. on Haemopoiesis (edit. by Wolstenholme, G. E. W., and O'Connor, M.), 185 (Churchill, London, 1960).
Corsi, A., and Giusti, G. V., Nature, 216, 493 (1967).
Miller, J. F. A. P., Block, M., Rowlands, D. T., and Kind, P., Proc. Soc. Exp. Biol. and Med., 118, 916 (1965).
Till, J. E., and McCulloch, E. A., Radiat. Res., 14, 213 (1961).
Mekori, T., and Feldman, M., Transplantation, 3, 98 (1965); Liron, M., and Feldman, M., Transplantation, 3, 509 (1965).
Siminovitch, L., McCulloch, E. A., and Till, J. E., J. Cell Comp. Physiol., 62, 327 (1963).
Becker, A. J., McCulloch, E. A., and Till, J. E., Nature, 197, 452 (1963).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
TRAININ, N., RESNITZKY, P. Influence of Neonatal Thymectomy on Cloning Capacity of Bone Marrow Cells in Mice. Nature 221, 1154–1155 (1969). https://doi.org/10.1038/2211154a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/2211154a0
This article is cited by
-
The potential of interleukin-17 to mediate hematopoietic response
Immunologic Research (2012)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
