Abstract
IT is generally believed that genetic transcription is carried out by an enzyme, DNA-dependent RNA polymerase1, which is capable of copying DNA sequences into RNA sequences. The enzyme requires DNA and the four naturally occurring ribonucleotide triphosphates to produce RNA which is a faithful copy of the DNA template2 in terms of base composition, nearest neighbour analysis and DNA–RNA hybridization3.
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TOCCHINI-VALENTINI, G., MARINO, P. & COLVILL, A. Mutant of E. coli containing an Altered DNA-dependent RNA Polymerase. Nature 220, 275–276 (1968). https://doi.org/10.1038/220275a0
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DOI: https://doi.org/10.1038/220275a0
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