Abstract
HUMAN serum alkaline phosphatase from some individuals can be separated by starch gel electrophoresis into two components. The faster moving zone has the electrophoretic characteristics of liver and bone alkaline phosphatase1 and, like liver alkaline phosphatase, it is only slightly inhibited by treatment with phenylalanine. By contrast, the slower moving zone has the electrophoretic characteristics of small intestinal alkaline phosphatase2,3 and its activity is markedly inhibited by phenylalanine4,5.
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References
Hodson, A. W., Latner, A. L., and Raine, L., Clin. Chim. Acta, 7, 255 (1962).
Robinson, J. C., and Pierce, J. E., Nature, 204, 472 (1964).
Moss, D. W., Eaton, R. H., Smith, J. K., and Whitby, L. G., Biochem. J., 98, 320 (1966).
Fishman, W. H., Green, S., and Inglis, N. I., Nature, 198, 685 (1963).
Kreisher, J. H., Close, V. A., and Fishman, W. H., Clin. Chim. Acta, 11, 122 (1965).
Arfors, K. E., Beckman, L., and Lundin, L. G., Acta Genet., 13, 89 (1963).
Arfors, K. E., Beckman, L., and Lundin, L. G., Acta Genet., 13, 366 (1963).
Beckman, L., Acta Genet., 14, 286 (1964).
Bamford, K. F., Harris, H., Luffman, J. E., Robson, E. B., and Cleghorn, T., Lancet, i, 530 (1965).
Shreffler, D. C., Amer. J. Hum. Genet., 17, 71 (1965).
Ahmed, Z., and King, E. J., Biochim. Biophys. Acta, 40, 320 (1960).
Morton, R. K., Nature, 172, 65 (1953).
Kind, P. R. N., and King, E. J., J. Clin. Pathol., 7, 322 (1954).
Boyd, W. C., and Shapleigh, E., Blood, 9, 1195 (1954).
Terpstra, T. J., Proc. Kon. Ned. Akad. Wetenschap. A55 (Indagationes Mathematicae, 14), 327 (1952), quoted by Noether, G. E., Elements of Nonparametric Statistics (J. Wiley, London, 1967).
Langman, M. J. S., Leuthold, E., Robson, E. B., Harris, J., Luffman, J. E., and Harris, H., Nature, 212, 41 (1966).
Inglis, N. I., Krant, M. J., and Fishman, W. H., Proc. Soc. Exp. Biol. and Med., 124, 699 (1967).
Klein, U. E., Drube, H. C., and Hansen, H. T., Klin. Wschr., 45, 95 (1967).
Shreffler, D. C., Proc. Soc. Exp. Biol. and Med., 123, 423 (1966).
Blankenhorn, D. H., Jensen, J., Sturgeon, P., Chin, H. P., Armstrong, B. W., and Engelman, L., Nature, 215, 1499 (1967).
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LANGMAN, M., CONSTANTINOPOULOS, A. & BOUCHIER, I. ABO Blood Groups, Secretor Status, and Intestinal Mucosal Concentrations of Alkaline Phosphatase. Nature 217, 863–865 (1968). https://doi.org/10.1038/217863a0
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DOI: https://doi.org/10.1038/217863a0
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