Abstract
The blood-bathed organ technique, which allows the continuous bioassay of substances in the circulating blood, has been used to measure the half lives of several substances in the circulation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Chadhury, R. R., and Walker, J. M., J. Physiol., 138, 50P (1957).
Silver, L., Schwartz, I. L., Fong, C. R. O., Debons, A. F., and Dahl, L. K., J. Appl. Physiol., 16, 1097 (1961).
Share, L., Amer. J. Physiol., 203, 1179 (1962).
Whitby, L. G., Axelrod, J., and Weil-Malherbe, H., J. Pharmacol. Exp. Ther., 132, 193 (1961).
Saameli, K., and Eskes, T. K. A. B., Amer. J. Physiol., 203, 351 (1962).
Gillespie, J. S., and Muir, T. C., Brit. J. Pharmacol. Chemother., 30, 88 (1967).
Sawyer, W. H., Pharm. Rev., 13, 225 (1961).
Sawyer, W. H., Chan, W. Y., and Van Dyke, H. B., Endocrinology, 71, 536 (1962).
Vane, J. R., Brit. J. Pharmacol. Chemother., 23, 360 (1964).
Hodge, R. L., Lowe, R., and Vane, J. R., J. Physiol., 185, 613 (1966).
Hodge, R. L., Lowe, R., and Vane, J. R., Nature, 211, 451 (1966).
Piper, P., Collier, H. O. J., and Vane, J. R., Nature, 213, 838 (1967).
Ferreira, S. H., and Vane, J. R., Brit. J. Pharmacol. Chemother., 29, 367 (1967).
Regoli, D., and Vane, J. R., Brit. J. Pharmacol. Chemother., 23, 351 (1964).
Vane, J. R., Brit. J. Pharmacol. Chemother., 12, 344 (1957).
Gaddum, J. H., Brit. J. Pharmacol. Chemother., 8, 321 (1953).
Paton, W. D. M., J. Physiol., 137, 35P (1957).
Gonzales-Panizza, V. H., Sica-Blanco, Y., and Mendez-Bauer, C. (edit. by Caldero-Barcia, R.), 347 (Pergamon Press, Oxford, 1961).
Ginsburg, M., and Smith, M. W., Brit. J. Pharmacol. Chemother., 14, 327 (1959).
Saxby, O. B., Siddiqi, S., and Walker, J. M., J. Physiol., 153, 6P (1960).
Spector, W. S., Handbook of Biological Data, 285 (Saunders, Philadelphia, London, 1956).
Ferreira, S. H., and Vane, J. R., Brit. J. Pharmacol. Chemother., 30, 417 (1967).
Eisen, V., and Keele, C. A. (edit. by Erdös, E. G.), 551 (Springer Verlag, NY, 1966).
Oates, T. A., and Melmon, K. L. (edit. by Erdös, E. G.), 565 (Springer Verlag, NY, 1966).
Hodge, R. L., Ng, K. K. F., and Vane, J. R., Nature, 215, 138 (1967).
Regoli, D., and Vane, J. R., J. Physiol., 183, 513 (1966).
Vane, J. R., Pharm. Rev., 18, 317 (1966).
Elliot, T. R., J. Physiol., 32, 401 (1905).
Markowitz, J., and Mann, F. C., Amer. J. Physiol., 89, 176 (1929).
Starling, E. H., and Verney, E. B., Proc. Roy. Soc., B, 97, 321 (1925).
Gaddum, J. H., Hebb, C. O., Silver, A., and Swan, A. B., Quart. J. Exp. Physiol., 38, 255 (1953).
Davis, R. B., and Wang, Y., Proc. Soc. Exp. Biol. and Med., 118, 797 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
FERREIRA, S., VANE, J. Half-lives of Peptides and Amines in the Circulation. Nature 215, 1237–1240 (1967). https://doi.org/10.1038/2151237a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/2151237a0
This article is cited by
-
Stress (Takotsubo) cardiomyopathy—a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning
Nature Clinical Practice Cardiovascular Medicine (2008)
-
Simultaneous31P- and1H-Nuclear Magnetic Resonance Studies of Hypoxia and Ischemia in the Cat Brain
Journal of Cerebral Blood Flow & Metabolism (1987)
-
New approaches to the creation of antihypertensive drugs using inhibitors of angiotensin II formation (review)
Pharmaceutical Chemistry Journal (1984)
-
The neuroendocrine response to multiple trauma
World Journal of Surgery (1983)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.