Abstract
IT is the orthodox view that circulating thyroid hormone consists mainly of thyroxine (T4), together with small amounts of triiodothyronine (T3), while the iodotyrosines account for only 0–4 per cent of the total organic iodine1–4. There have been reports5–8, however, that the iodotyrosines account for 30–50 per cent of the iodine in normal human blood. In the condition of thyrotoxicosis, quite large amounts of diiodotyrosine (DIT) are detected in the plasma, although the amount has not yet been precisely quantitated3,4,9.
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O'HALLORAN, M., WELLBY, M. Recoveries of Iodine-131-labelled Iodo-amino-acids in the Plasma Protein-bound Iodine Assay. Nature 211, 1195–1197 (1966). https://doi.org/10.1038/2111195b0
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DOI: https://doi.org/10.1038/2111195b0
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