Abstract
IN earlier investigations we evaluated directly the adrenal 17-hydroxycorticosteroid (17-OHCS) secreted in response to histamine by unanaesthetized dogs1. Marked increase in 17-OHCS secretion was observed after injection of histamine. It has been suggested by some authors that histamine is released from mammalian cells in anaphylactic shock. Very little experimental information is available, however, on the effect of anaphylactic shock on the adrenal cortical secretion. In the present investigations we attempted to evaluate directly the adrenal 17-OHCS secretion in response to anaphylactic shock in unanaesthetized and anaesthetized dogs.
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SUZUKI, T., HIRAI, K., OTSUKA, K. et al. Anaphylactic Shock and the Secretion of Adrenal 17-Hydroxycorticosteroid in the Dog. Nature 211, 1185–1186 (1966). https://doi.org/10.1038/2111185a0
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DOI: https://doi.org/10.1038/2111185a0
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