Abstract
THE cell membranes of various tumour strains possess large quantities of sialic acid and a strong, negative surface charge1–5. This charge, which is partly due to the ionized carboxyl group of sialic acid2,4,5, may be important in influencing physiological properties such as transport of ions6. Since tumour cells seem to concentrate K+ ions better than normal cells7–9, we have begun to investigate the regulation of K+ fluxes by sialic acid.
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GLICK, J., GITHENS, S. Role of Sialic Acid in Potassium Transport of L1210 Leukaemia Cells. Nature 208, 88 (1965). https://doi.org/10.1038/208088a0
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DOI: https://doi.org/10.1038/208088a0
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