Abstract
THE importance of nucleoproteins in antibody-globulin production is well known1,2. In previous experiments3,4 an evident increase of the content of RNA in the γ-globulin fraction in immune sera has been observed. The RNA extracted from the serum of immunized rabbits is capable of eliciting in normal rabbits the production of antibodies against the same antigens used for immunizing the animals from which this RNA-immuno-carrier (RNA-I-C) was taken. The following investigations were undertaken to ascertain whether an RNA-I-C extracted from the serum of immunized animals of one species was able to induce antibody production in animals of a different species.
Similar content being viewed by others
Article PDF
References
Michelazzi, L., Boll. Ist. Sier. Mil., 29, 28 (1950).
Fishman, M., and Adler, F. L., J. Exp. Med., 117, 595 (1963).
Michelazzi, L., Nanni, G., and Baldini, I., Reported to Meeting, Soc. Ital. Biol. Sperim. (March 25, 1964).
Michelazzi, L., Nanni, G., Baldini, I., and Novelli, A., Experientia, 20, 447 (1964).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MICHELAZZI, L., BALDINI, I., NOVELLI, A. et al. Immune Response induced by RNA-Immuno-carrier extracted from Heterologous Immune Sera. Nature 205, 194 (1965). https://doi.org/10.1038/205194a0
Published:
Issue Date:
DOI: https://doi.org/10.1038/205194a0
This article is cited by
-
Inhibition of antibody production in rats and mice by intravenous injection of interferon-inducing amounts of Sindbis virus or E. Coli
Archiv f�r die gesamte Virusforschung (1967)
-
Induction of anti-Treponema pallidum antibodies in normal rabbits by RNA-immuno-carrier extracted from serum of syphilitic rabbits
Experientia (1967)
-
Precocious Anti-diphtheria Response induced by RNA Immuno-carrier
Nature (1965)
-
Induction of antibody response in lymphoid cells in vivo and in vitro by RNA-immuno-carrier from immune serum
Experientia (1965)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.