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Calcium–Strontium Discrimination in Miniature Pigs as Related to Age

Nature volume 202, pages 104–106 (1964)Cite this article

Abstract

A GREAT deal of work, summarized in a recent United Nations document1, has indicated the preferential incorporation into the skeleton of calcium relative to strontium-90. Work in our laboratory with miniature pigs has shown that the young animal has a decreased discrimination against 90Sr relative to calcium for movement of these elements from diet to skeleton2. This finding was based on a comparison of the 90Sr and calcium content of the skeleton and the diet of pigs ingesting 90Sr daily in a long-term study on the biological effects of 90Sr in miniature pigs3,4. Since these animals were ingesting 90Sr each day, and animals were killed only at birth, weaning, 3 months, and older, it was not possible to demonstrate clearly the progressive change in calcium–90Sr discrimination with age. The work reported here was performed to clarify the age-dependency of calcium–strontium discrimination.

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  1. Biology Laboratory, Hanford Laboratories, General Electric Company, Richland, Washington

    R. O. McCLELLAN

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  1. R. O. McCLELLAN
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McCLELLAN, R. Calcium–Strontium Discrimination in Miniature Pigs as Related to Age. Nature 202, 104–106 (1964). https://doi.org/10.1038/202104a0

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