Abstract
IN diencephalic stimulation experiments of Suzuki et al.1 a definite decrease in 17-hydroxycorticosteroid (17-OHCS) secretion rate was observed in one dog after stimulation of the pre-optic area. Similar observation was made in one cat with éncephale isolé by Slusher and Hyde2. These observations suggested a possible inhibitory effect of preoptic stimulation on the pituitary-adrenocortical function. However, since they were made only on one dog and on one cat, many more experiments seem to be necessary before this problem can be settled. The present investigation was undertaken in order to settle this problem.
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References
Suzuki, T., Romanoff, E. B., Koella, W. P., and Levy, C. K., Amer. J. Physiol., 198, 1312 (1960).
Slusher, M. A., and Hyde, J. E., Endocrinology, 69, 1080 (1961).
Suzuki, T., and Arai, T., Tohoku J. Exp. Med., 58, 105 (1953).
Egdahl, R. H., Nelson, D. H., and Hume, D. M., Science, 121, 506 (1955).
Nelson, D. H., and Samuels, L. T., J. Clin. Endocrinol., 12, 519 (1952).
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YOSHIO, H. Inhibitory Effect of Pre-optic Stimulation on Adrenal 17-Hydroxycorticosteroid Secretion Rate in the Cat. Nature 201, 1334–1335 (1964). https://doi.org/10.1038/2011334b0
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DOI: https://doi.org/10.1038/2011334b0
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