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Mole Ratios of the Neurohypophysial Hormones in the Vertebrate Neural Lobe

Abstract

THE ratio of the pressor-antidiuretic to oxytocic activity in extracts of mammalian posterior pituitary glands has often been used to express the ratio of the hormones present. Such calculations seem admissible since vaso-pressin has only a small oxytocic activity and oxytocin a small pressor-antidiuretic activity1,2; moreover, the molecular weights of the two peptides are nearly identical. Similar calculations cannot, however, be applied to non-mammalian vertebrates.

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FOLLETT, B. Mole Ratios of the Neurohypophysial Hormones in the Vertebrate Neural Lobe. Nature 198, 693–694 (1963). https://doi.org/10.1038/198693a0

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