Abstract
THE toxicity of allylic and acetylenic halides to larvae of the citrus nematode has been shown to be related to their reactivities in the bimolecular nucleophilic substitution reaction (SN2) with potassium iodide in acetone1, which suggested that these compounds kill by combining irreversibly with essential nucleophilic centres, such as sulphydryl groups, in the nematode. Other factors which were also involved in the toxicity of these halides were their rates of hydrolysis in water and the toxicities of the resulting alcohols.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Moje, W., J. Agric. Food Chem., 7, 702 (1959).
Crowell, T. I., J. Amer. Chem. Soc., 75, 6046 (1953).
Roudier, L., C.R. Acad. Sci., Paris, 245, 2296 (1957).
Finney, D. J., Probit Analysis, second ed. (Camb. Univ. Press, London, 1952).
Fierens, P. J. C., and Vershelden, P., Bull. soc. chim. Belges, 61, 427 (1952).
Tutwiler, F. B., and McKee, R. L., J. Amer. Chem. Soc., 76, 6342 (1954).
Wright, W. H., Schaffer, J. M., Bozicevich, J., and Underwood, P. C., Papers on Helminthology, 30-year Jubileum of K. I. Skrjabin, 769 (Government U.S.S.R., 1937).
Hassel, K. A., J. Sci. Food Agric., 7, 415 (1957).
Baechler, R. H., Proc. Amer. Wood-preservers Assoc., 43, 94 (1947).
Ferguson, J., Proc. Roy. Soc., B, 127, 387 (1939).
Ferguson, J., and Pirie, H., Ann. App. Biol., 35, 532 (1948).
Hassel, K. A., Ann. App. Biol., 40, 688 (1953).
Rang, H. P., Brit. J. Pharmacol., 15, 185 (1960).
Overberger, C. G., and Bonsignore, P. V., J. Amer. Chem. Soc., 80, 5431 (1958).
Bray, H. G., and James, S. P., Biochem. J., 74, 6, P (1961).
James, S. P., Biochem. J., 80, 4 P (1961).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MOJE, W. Toxicity of Some n-Alkyl Bromides to Larvæ of the Citrus Nematode. Nature 198, 608–609 (1963). https://doi.org/10.1038/198608a0
Issue Date:
DOI: https://doi.org/10.1038/198608a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
