Abstract
PLASMA kinin formation1 can be induced by treating plasma in a variety of ways, excluding the addition of proteolytic enzymes. In our present work the procedures which we have applied to ‘pre-active’ human plasma or serum include exposure to a large glass surface2, addition of ε-amino-caproic acid or disodium edetate3, dilution4, re-suspension of the 33 per cent saturated ammonium sulphate precipitate, or addition of the purified kinin-forming material isolated from human plasma (Armstrong, D., and Mills, G. L., unpublished work).
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ARMSTRONG, D., STEWART, J. Anti-Heparin Agents as Inhibitors of Plasma Kinin Formation. Nature 194, 689 (1962). https://doi.org/10.1038/194689a0
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DOI: https://doi.org/10.1038/194689a0
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