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Structure of Lathyrine

Abstract

IN a preliminary report1 the isolation of a new amino-acid, giving a red colour with ninhydrin, from seeds of Lathyrus tingitanus was described. The molecular formula was given as C7H10O2N4 and the apparent pKa values of its one carboxyl and two proton accepting groups as 2.4, 4.1 and 9.0. The compound showed an absorption maximum, varying with pH between 285 and 300 mµ, which disappeared when an aqueous solution of the amino-acid sulphate was hydrogenated over Adam's catalyst. The reduced compound contained a guanidino or substituted guanidino group and gave a purple colour with ninhydrin.

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References

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BELL, E., FOSTER, R. Structure of Lathyrine. Nature 194, 91–92 (1962). https://doi.org/10.1038/194091a0

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  • DOI: https://doi.org/10.1038/194091a0

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