A New Anthelmintic with Unusual Properties

Abstract

DURING studies on anthelmintic activity which have been in progress in these laboratories during the past few years, we have encountered an interesting degree of activity among a limited number of substituted pyridines. Nothing of practical value emerged from the early observations, but they caused us to retain an interest in related substances. Recently, through the courtesy of The Midland Tar Distillers, Ltd., we had the opportunity of examining some pyridine compounds made in their Research and Development Department, and one of them, prepared by Mr. P. Araall, has proved of exceptional interest. This compound is 2-(β-methoxyethyl)-pyridine (U.K. Patent Application 40845/59 ; 40931/59 ; 20099/60) : It is a liquid and extremely soluble in water.