Abstract
PREVIOUS work in this laboratory has given support to the conclusion that the brain lesion in neonatal bilirubin encephalopathy or kernicterus is primarily due to a toxic effect of free bilirubin on cellular energy metabolism1. Hæmolytic diseases in new-born children, resulting in severe hyperbilirubinæmia, may therefore lead to the development of kernicterus, regardless of the cause of the hæmolysis.
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BROBERGER, O., ERNSTER, L. & ZETTERSTRÖM, R. Oxidation of Human Hæmoglobin by Vitamin K3 . Nature 188, 316–317 (1960). https://doi.org/10.1038/188316a0
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DOI: https://doi.org/10.1038/188316a0
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