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Ultrastructure of the Clear Cells in Renal Carcinomas and its Importance for the Demonstration of their Renal Origin

Abstract

MOST pathologists will agree that the histogenesis of the so-called Grawitz tumours of the kidney was settled by the classical paper of Stoerk published in 19081; but the arguments of this author, convincing as they were in disproving the suprarenal nature of the ‘hypernephroma’, were much less so in demonstrating their renal origin. That is the reason why this latter opinion has been challenged time and again. New theories have been put forward, among which those of Apitz2 and of Feyrter3 have attracted some attention lately.

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References

  1. Stoerk, O., Beitr. Anat. und Allg. Path., 43, 393 (1908).

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  2. Apitz, K., Virch. Arch., 311, 285 (1943).

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  3. Feyrter, F., “Über diffuse endokrine epitheliale Organe” (J. A. Barth, Leipzig, 1938).

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  4. Pease, D. C., J. Biophys. Biochem. Cytol., 2 (Supp.), 203 (1956).

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OBERLING, C., RIVIÈRE, M. & HAGUENAU, F. Ultrastructure of the Clear Cells in Renal Carcinomas and its Importance for the Demonstration of their Renal Origin. Nature 186, 402–403 (1960). https://doi.org/10.1038/186402a0

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