Abstract
IT has been reported that, with renal hypertension, retention of sodium and loss of potassium occurred in the musculature1–4 and that the same changes in electrolyte metabolism appear after application of hypertension-inducing corticosteroids5–9. Therefore these alterations in the inorganic metabolism were considered to be the direct cause of hypertension10,11. Tobian et al. 12 found an increase in sodium, potassium and water content of the aorta in all forms of experimental hypertension and concluded this to be the cause of hypertension.
Similar content being viewed by others
Article PDF
References
Eichelberger, L., J. Exp. Med., 77, 205 (1943).
Laramore, D. C., and Grollman, A., Amer. J. Physiol., 161, 278 (1950).
Leonards, J. R., and Heisler, C. R., Fed. Proc., 11, 247 (1952).
Orbison, J. L., Christian, C. L., and Peters, E., Arch. Path., 54, 185 (1952).
Selye, H., Hall, C. E., and Rowley, E. M., Canad. Med. Assoc. J., 49, 88 (1943).
Thorn, G. W., Engel, L. L., and Eisenberg, H., J. Exp. Med., 68, 161 (1938).
Thorn, G. W., Engel, L. L., and Eisenberg, H., Bull. Hopkins Hosp., 64, 155 (1939).
Gaunt, R., Birnie, J. H., and Eversole, W. J., Physiol. Rev., 29, 281 (1949).
Overman, R. R., Physiol. Rev., 31, 285 (1951).
Braun-Menendez, E., and Covian, M. R., Rev. Soc. arg. Biol., 24, 31 (1948).
Braun-Menendez, E., Ciba Fondation Symposium on Hypertension, 238 (Churchill, London, 1954).
Tobian, L., and Binion, J. T., J. Clin. Invest., 33, 1407 (1954). Tobian, L., and Redleaf, P. D., Amer. J. Physiol., 192, 325 (1958); 189, 451 (1957). Tobian, L., and Binion, J. T., Circulation, 5, 754 (1952).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LASZT, L. Correlation between the Electrolyte and Water Content of the Organs and Hypertension after Administration of Corticosteroids. Nature 185, 695 (1960). https://doi.org/10.1038/185695a0
Issue Date:
DOI: https://doi.org/10.1038/185695a0
This article is cited by
-
Effect of Different Vasomotor Agents on the Visco-elastic Behaviour of Arteries of the Muscular Type
Nature (1963)
-
Properties of Vessel Muscle Proteins extracted with Water or Salt Solutions of Low Ionic Strength
Nature (1961)
-
Effect of the Cations of the Lyotropic Series on the Tension of Vascular Muscle
Nature (1960)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.