Abstract
THE presence of metals in highly purified protein preparations is of considerable interest. The paramount part played by metals, especially in enzyme reactions (see, for example, ref. 1), is well known. Besides the specific metals in the metalloproteins, most proteins are able to bind, more or less firmly, metals removed from the medium. The removal of metals from a protein solution may be an important preliminary step in a study of its properties and structure. Unfortunately, the available methods for the detection of metals involve the use of very expensive equipment, or are laborious, and require large quantities of protein.
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MILSTEIN, C. A Simple Test for the Presence of Metals in Biological Materials. Nature 185, 386–387 (1960). https://doi.org/10.1038/185386b0
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DOI: https://doi.org/10.1038/185386b0
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