Abstract
IT has previously been demonstrated that oximino compounds are widely distributed in organisms1, and that two enzymes, named oximase2 and transoximase3, which participate in oxime metabolism, exist in some animals. In pursuing the behaviour of hydroxylamine in living cells, we have now established that there is an enzymatic cycle between ammonia and nitrate.
Similar content being viewed by others
Article PDF
References
Yamafuji, K., Kondo, H., and Omura, H., Enzymologia, 14, 153 (1950).
Yamafuji, K., Nature, 167, 770 (1950). Yamafuji, K., Aoki, M., and Omura, H., Enzymologia, 17, 371 (1956).
Yamafuji, K., Nature, 171, 745 (1953). Yamafuji, K., and Eto, M., Enzymologia, 16, 247 (1953).
Medina, A., and Nicholas, D. J. D., Nature, 179, 533 (1957).
Taniguchi, S., Sato, R., and Egami, F., “Symposium on Inorganic Nitrogen Metabolism”, edit. by McElroy, W. D., and Glass, B., 87 (Johns Hopkins Press, 1956).
Zucker, M., and Nason, A., J. Biol. Chem., 213, 463 (1955).
Klausmeier, R. E., and Bard, R. C., J. Bacteriol., 68, 129 (1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
YAMAFUJI, K., OSAJIMA, Y. & OMURA, H. Enzymatic Cycle of Inorganic Nitrogen in Animal Tissues. Nature 185, 162 (1960). https://doi.org/10.1038/185162a0
Issue Date:
DOI: https://doi.org/10.1038/185162a0
This article is cited by
-
Mutagenic Action of Hyponitrous Acid and Glucose Oxime
Nature (1964)
-
A Gene synthesizing Deoxyribonuclease in the Polyhedral Pre-viral Genome
Nature (1962)
-
Ammonia Dehydrogenase, Hydroxylamine Dehydrogenase, Hyponitrite Dehydrogenase and Nitrite Dehydrogenase
Nature (1961)
-
Enzymatic Reduction of Diphosphopyridine Nucleotide with Urea
Nature (1961)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.