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Electron Microscope Studies of the Structure of the Influenza Virus

Abstract

FROM studies of the growth-cycle of influenza virus, Hoyle1,2 formed the hypothesis that the virus elementary body consisted of an aggregate of smaller units, and Burnet and Lind3 arrived at a similar concept from studies of virus variation. Hoyle2,4 showed that the virus could be disintegrated by shaking with ether, with the production of separate red-cell agglutinating and complement-fixing particles of smaller size than that of the elementary body.

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References

  1. Hoyle, L., Brit. J. Exp. Path., 29, 390 (1948).

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  2. Hoyle, L., J. Hygiene Camb., 48, 277 (1950).

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  3. Burnet, F. M., and Lind, P. E., J. Gen. Microbiol., 5, 67 (1951).

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  4. Hoyle, L., J. Hygiene Camb., 50, 229 (1952).

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HOYLE, L., REED, R. & ASTBURY, W. Electron Microscope Studies of the Structure of the Influenza Virus. Nature 171, 256–257 (1953). https://doi.org/10.1038/171256b0

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