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Response to Martino and Cordonnier

Bone Marrow Transplantation volume 31, page 619 (2003)Cite this article

Martino and Cordonnier, quiet rightly, draw attention to the EBMT-IDWP 5 year survey of toxoplasmosis, which adds a large number of cases to the literature. The full paper was published in November 2000 and, although our literature search included papers with publication dates up to December 2000, we regret that this did not pick up this reference. Some of their cases (although it is not clear how many) appear to have been reported before (eg Bretagne et al,1 and some of these were included in our review.

As we noted in the paper, the diagnosis of toxoplasmosis is often difficult in these patients and we welcome the development of a set of consensus case definitions. We would support this approach for use in studies of toxoplasmosis and other conditions (as has been developed for invasive fungal infections, for example2) in these patients.

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References

  1. Bretagne S, Costa JM, Kuentz M et al. Late toxoplasmosis evidenced by PCR in a marrow transplant recipient. Bone Marrow Transplant 1995; 15: 809–811.

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  2. Ascioglu S, Rex JH, de Pauw B et al. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis 2002; 34: 7–14.

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  3. McHugh TD, Ramsay AR, James EA et al. Pitfalls of PCR: misdiagnosis of cerebral nocardia infection. Lancet 1995; 346: 1436.

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Authors and Affiliations

  1. Departments of Medical Microbiology and Haematology Royal Free & University College Medical School Royal Free Campus, Rowland Hill Street, London, NW3 2PF, UK

    C C Kibbler, A Mele, P J Paterson & H G Prentice

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  1. C C Kibbler
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  2. A Mele
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  3. P J Paterson
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  4. H G Prentice
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Kibbler, C., Mele, A., Paterson, P. et al. Response to Martino and Cordonnier. Bone Marrow Transplant 31, 619 (2003). https://doi.org/10.1038/sj.bmt.1703915

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