Abstract
MEGAMOLECULAR crystals such as the crystals of native proteins confront X-ray crystallography with a new situation, since the structure of the molecules is unknown. We suggest that a systematic study of what may be called the language of structure factors may be a useful, even a necessary, preliminary to the interpretation of the intensity maps of crystals containing megamolecules of unknown structure. A preliminary study of this nature has therefore been undertaken1. The purpose of this note is to describe one by-product of this work which may be of interest in view of the great prominence given to the Patterson diagrams of protein crystals, namely, a method of evaluating the Patterson distribution of a given distribution.
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References
"Fourier Transforms and Structure Factors." American Society for X-Ray and Electron Diffraction Monograph, No. 2 (in course of publication).
Courant, R., "Differential and Integral Calculus," 2, 318 (Nordemann Publishing Company, New York. 1936).
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WRINCH, D. Patterson Distributions and Native Protein Crystallography. Nature 157, 226 (1946). https://doi.org/10.1038/157226a0
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DOI: https://doi.org/10.1038/157226a0
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